Copper based nanomaterials for potential biomedical applications
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The current thesis work emphasizes on fabrication of different nanoscale dimensions of copper and manipulating them with different materials for diverse biomedical applications. As a relatively safe material with wide functionality; copper was chosen as a primary platform to fabricate some therapeutic tools. The present thesis is divided into six chapters.Chapter 1 of the thesis describes about nanoscience and nanotechnology. It also provides information about nanomaterials along with their synthesis and multi-dimensional applications. Salient features of this current thesis work have been mentioned in brief.Chapter 2 explains a facile process of fabrication of a luminescent bovine serum albumin (BSA)-copper nanocluster (BSA-Cu NCs) customized ibuprofen nanodrug (BSA-Cu NC-Ibf) for in vivo cancer therapy as malignancy has covered a major portion of the health ailments of our society. The as synthesized BSA-Cu NC-Ibf exhibited incomparable chemotherapeutic efficiency on Daltons lymphoma ascites (DLA) bearing Swiss albino mice with significant reduction of tumour growth. It also inhibited metastasis of the cancer cells and thus enhances the life expectancy of mice.
Supervisors: Siddhartha Sankar Ghosh and Arun Chattopadhyay