Development of novel sulfonium containing drug carriers with inherent antimicrobial activities to combat drug resistance

Abstract

This Thesis title “Development of novel sulfonium containing drug carriers with inherent antimicrobial activities to combat drug resistance” deals with the study of sulfonium containing liposome and polymers which contains membrane directed bactericidal activity and hence it can counteract different drug resistance mechanism of the drug resistance due to efflux transporter, reduced number of porins, metabolic drug inactivation and hence it can rejuvenate the activity of the clinically proven antibiotics against drug resistant bacterial strains