Study of copper(II) based Oxidative C-H Functionalization/C-C/N-N/C-O Bonds Formation for synthesis of Substituted Azole
| dc.contributor.author | Guru, Murall Mohan | |
| dc.date.accessioned | 2015-09-16T12:14:45Z | |
| dc.date.accessioned | 2023-10-19T12:14:11Z | |
| dc.date.available | 2015-09-16T12:14:45Z | |
| dc.date.available | 2023-10-19T12:14:11Z | |
| dc.date.issued | 2012 | |
| dc.description | Supervisor: T. Punniyamurthy | en_US |
| dc.description.abstract | The thesis contains four chapters. The first two chapters focus on the copper(II) based synthesis of 2-arylbenzoxazoles and 2-aryl-N-benzylbenzimidazoles from bisaryloxime ethers and N-benzylbisarylhydrazones via C functionalization/C bonds formation. The last two chapters deal with the copper(II)-catalyzed aerobic oxidative synthesis of substituted 1,2,3- and 1,2,4-triazoles from bisarylhydrazones via C bonds formation. 1. Synthesis of 2-Arylbenzoxazoles from Bisaryloxime Ethers via C Bonds Formation Benzoxazoles are an important class of heterocycles that are encountered in a number of biologically active natural products and medicinally significant compounds. This chapter describes an unprecedented copper(II)-catalyzed conversion of bisaryloxime ethers to 2- arylbenzoxazoles in presence of molecular oxygen at 80 ओC under ligand-free condition (Scheme 1). This process involves a cascade C functionalization/C bonds formation. The substrates bearing electron-withdrawing or electron-donating groups in the arenes proceeded reaction smoothly to provide the corresponding benzoxazoles in moderate to high yields.. | en_US |
| dc.identifier.other | ROLL NO.09612222 | |
| dc.identifier.uri | https://gyan.iitg.ac.in/handle/123456789/340 | |
| dc.language.iso | en | en_US |
| dc.relation.ispartofseries | TH-1134; | |
| dc.subject | CHEMISTRY | en_US |
| dc.title | Study of copper(II) based Oxidative C-H Functionalization/C-C/N-N/C-O Bonds Formation for synthesis of Substituted Azole | en_US |
| dc.type | Thesis | en_US |