Exploration of Self-Assembly in Short Peptides for the Development of Useful Functional Materials

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dc.contributor.authorDowari, Payel
dc.date.accessioned2023-06-01T11:31:06Z
dc.date.accessioned2023-10-19T12:12:32Z
dc.date.available2023-06-01T11:31:06Z
dc.date.available2023-10-19T12:12:32Z
dc.date.issued2022
dc.descriptionSupervisor: Das, Debapratimen_US
dc.description.abstractThe thesis on ‘Exploration of Self-Assembly in Short Peptides for the Development of Useful Functional Materials’ deals with the design of novel short peptides, studying their self assembly behaviour with the different non-covalent interactions, and exploring their possible applications in the field of peptide-based functional materials. Chapter 1 is a brief introduction on peptide-based nanomaterials and their various applications with sufficient literature review. Chapter 2 describes the development of a thixotropic hydrogel using the self-aggregation of a peptide amphiphile. Chapter 3 describes the successful utilization of the technique of peptide coassembly for the formulation of a functional peptide hydrogel for aiming localized drug-delivery through receptor mediated cellular internalization mechanisms. Chapter 4 deals in development of a multi-stimuli responsive cross-linked peptide polymer using different cross-linking methodologies, for attaining size-tunability property and controlled cell-proliferation. Chapter 5 deals in development of an artificial hydrolase. The work involves systematic design and immobilization of a hydrolase-like short peptide amphiphile on silica surfaces for enhancement of extent of catalysis, improvement of catalyst stability and increased stereoselectivity, compared to the micellar aggregates.en_US
dc.identifier.otherROLL NO.166122039
dc.identifier.urihttps://gyan.iitg.ac.in/handle/123456789/2376
dc.language.isoenen_US
dc.relation.ispartofseriesTH-2872;
dc.subjectPeptideen_US
dc.subjectSelf-Assemblyen_US
dc.subjectHydrogelen_US
dc.titleExploration of Self-Assembly in Short Peptides for the Development of Useful Functional Materialsen_US
dc.typeThesisen_US
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