Structural, Functional and Morphological Modifications of Graphene Oxide-based Nanocarriers for Anticancer Drug Delivery

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dc.contributor.authorSonatakke, Ankush Dasharath
dc.date.accessioned2024-12-12T11:35:30Z
dc.date.available2024-12-12T11:35:30Z
dc.date.issued2024
dc.descriptionSupervisor: Purkait, Mihir Kumar
dc.description.abstractChemotherapy has continued to be the most frequently utilized therapy for cancer treatment. Despite the abundance of chemical chemotherapeutic agents and anticancer medications, their unregulated administration and inability to distinguish between rapidly proliferating healthy cells and cancer cells lead to adverse impacts on cancer therapeutics. Moreover, due to the diversity of cancer cells, the emergence of drug resistance, and the undesirable effects induced by high and/or repetitive drug doses, the administration of a solitary chemotherapeutic agent frequently fails to accomplish a comprehensive cancer regression. The major challenges related to effective and sustainable consumption of chemotherapeutic agents can be subsided with targeted drug delivery systems (DDS) directed by the advanced nanomaterials (nanocarriers), natural chemotherapeutic agents such as gallic acid (GA), caffeic acid (CA), targeting ligands such as folic acid (FA) and employing co-delivery systems for chemotherapeutic agents. Previous studies related to anticancer DDS have demonstrated the therapeutic potential of graphene-based nanocarriers due to their distinct surface characteristics.
dc.identifier.otherROLL NO.176107025
dc.identifier.urihttps://gyan.iitg.ac.in/handle/123456789/2752
dc.language.isoen
dc.relation.ispartofseriesTH-3329
dc.titleStructural, Functional and Morphological Modifications of Graphene Oxide-based Nanocarriers for Anticancer Drug Delivery
dc.typeThesis
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