Syntheses of N-heterocycles via arene functionalization of nitrosoarenes
dc.contributor.author | Purkait, Anisha | |
dc.date.accessioned | 2023-04-11T08:27:23Z | |
dc.date.accessioned | 2023-10-19T12:12:25Z | |
dc.date.available | 2023-04-11T08:27:23Z | |
dc.date.available | 2023-10-19T12:12:25Z | |
dc.date.issued | 2021 | |
dc.description | Supervisor: Jana, Chandan K | en_US |
dc.description.abstract | Nitrosoarene is a versatile reagent for incorporation of N, O-functionality. However, the use of arene moiety in the reaction is not widely explored. Development of new protocols where the involvement of -N=O group as well as the arene moiety of nitrosoarene are applied towards the syntheses of valuable bio-active scaffolds is highly desirable. The contents of this thesis entitled “Syntheses of N-heterocycles via arene functionalization of nitrosoarenes” have been divided into six chapters. A brief review on different reactivity of nitrosoarene has been presented in the first chapter. Chapter 2 describes metal-free sequential C(sp2)−H and C(sp3)−H aminations of nitrosoarenes and N-heterocycles to ring-fused imidazoles. Chapter 3 presents N-aminations of benzylamines and alicyclic amines with nitrosoarenes to hydrazones and hydrazides. Chapter 4 describes Lewis-acid catalyzed pseudo three-component annulation of nitrosoarenes and (epoxy)styrenes to provide arylquinolines. Chapter 5 describes nitroso- ene reaction of nitrosoarene and azomethine to nitrones. The strategy has been applied for one-pot three component synthesis of oxazolidines and aryl quinolines. Finally, the experimental details and copies of 1H and 13C NMR data have been provided in chapter six. | en_US |
dc.identifier.other | ROLL NO.156122036 | |
dc.identifier.uri | https://gyan.iitg.ac.in/handle/123456789/2325 | |
dc.language.iso | en | en_US |
dc.relation.ispartofseries | TH-2801; | |
dc.subject | C(sp2)-H functionalization | en_US |
dc.subject | Nitrosoarenes Work | en_US |
dc.title | Syntheses of N-heterocycles via arene functionalization of nitrosoarenes | en_US |
dc.type | Thesis | en_US |
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