Development of ROS-responsive Turn-on Fluorogenic Prodrugs for the Delivery of Anti-inflammatory and Anti-cancer Drugs along with Hydrogen Sulfide

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creativework.keywordsKeywordsen
dc.contributor.authorSufian, Abu
dc.date.accessioned2024-12-05T11:28:57Z
dc.date.available2024-12-05T11:28:57Z
dc.date.issued2023
dc.descriptionSupervisor: Bhabak, Krishna P
dc.description.abstractMy PhD thesis titled “Development of ROS-responsive Turn-on Fluorogenic Prodrugs for the Delivery of Anti-inflammatory and Anti-cancer Drugs along with Hydrogen Sulfide” comprises of five chapters. In chapter 1, the mechanism of reactive oxygen species (ROS) production and detoxification in biological systems have been highlighted. In addition, the development of ROS-responsive fluorogenic probes, non-fluorogenic anti-inflammatory and anti-cancer prodrugs, and fluorogenic anti-cancer prodrugs have been reviewed elaborately. Moreover, the biological function, detection techniques, and enzymatic production of H2S have been discussed briefly. Several synthetic donors of H2S such as hydrolysis-based, biothiol-triggered, ROS-responsive, and so on have been reviewed briefly.
dc.identifier.otherROLL NO.176122050
dc.identifier.urihttps://gyan.iitg.ac.in/handle/123456789/2699
dc.language.isoen
dc.relation.ispartofseriesTH-3161
dc.titleDevelopment of ROS-responsive Turn-on Fluorogenic Prodrugs for the Delivery of Anti-inflammatory and Anti-cancer Drugs along with Hydrogen Sulfide
dc.typeThesis
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