Develppment of Hydroxyapatite Based Ceramic Composites and thin Films for Biomedical Applications
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Date
2022
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Abstract
Hydroxyapatite (Ca10(PO4)6(OH)2, HAP) is an immensely favored biomaterial in
the biomedical industry, known for its extensive applications in orthopedics and
dentistry. Naturally, it appears as an inorganic constituent of natural bones, with
substitutions like Mg, Sr, and other trace ions occupying the Ca sites. To distinguish
it from HAP, it is often designated as bone-like apatite or bone apatite in
brief. Consequently, it can be perceived that the Ca=P ratio of bone apatites di ers
from HAP (1.67 for HAP, whereas a ratio < 1.67 is obtained for bone apatite). The
last two decades have seen an exponential rise in the biomedical industry related
to HAP primarily due to its incredible biocompatibility, a nity to bond to living
bones when used as implants, and its ability to promote ingrowth of new bones
through osteoconduction without having any toxic or in
ammatory response to the
surrounding tissues. As a testimony to the claim, the recent reports published in
Yahoo nance claimed that the HAP market is projected to grow from USD 2.2
billion (currently in 2020) to USD 3.1 billion in 2025 at a compound annual growth
rate (CAGR) of 6.8%. It has been forecasted that the Asia-Paci c HAP market
will grow at the highest CAGR precisely due to the increase in medical tourism in
countries like India, South Korea, and Japan. It has led to the rapid development of
the domestic health care sector and is an indicator for exhaustive research in HAP
to develop devices and technologies to cater to growing medical tourism.
Description
Supervisor: Dobbidi, Pamu
Keywords
Ceramic, Composites, Biomaterials