(The) G-protein coupled estrogen receptor in breast tumors positively associates with ERalpha, and constitutes a clinically significant genomic target of estrogen in breast cancer cells

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dc.contributor.authorPal, Uttariya
dc.date.accessioned2023-07-19T07:27:04Z
dc.date.accessioned2023-10-19T11:07:18Z
dc.date.available2023-07-19T07:27:04Z
dc.date.available2023-10-19T11:07:18Z
dc.date.issued2023
dc.descriptionSupervisor: Limaye, Anil Mukunden_US
dc.description.abstractEstrogen exerts its effects on target cells, and tissues via genomic, and non-genomic pathways. The genomic effects of estrogen are mediated by the canonical estrogen receptors, namely ERα and ERβ. These are ligand-dependent transcription factors encoded by the ESR1 and ESR2 genes, respectively. The non-genomic effects of estrogen are mediated by membrane-tethered canonical estrogen receptors, ERα36, a splice variant of ERα, or the non-canonical G-protein coupled estrogen receptor (GPER).en_US
dc.identifier.otherROLL NO.166106001
dc.identifier.urihttps://gyan.iitg.ac.in/handle/123456789/2432
dc.language.isoenen_US
dc.relation.ispartofseriesTH-3154;
dc.subjectGPERen_US
dc.subjectER alphaen_US
dc.subjectTCGAen_US
dc.subjectBreast Tumoren_US
dc.subjectTamoxifenen_US
dc.title(The) G-protein coupled estrogen receptor in breast tumors positively associates with ERalpha, and constitutes a clinically significant genomic target of estrogen in breast cancer cellsen_US
dc.typeThesisen_US
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