Microbial Cell Factories for the Production of Recombinant Human Interferon Gamma
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Date
2016
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Abstract
IFN-γ is a dimerized, pleotropic cytokine and plays an important role in stimulating immune reactions. It is also critical for innate and adaptive immunity against viral and intracellular bacterial infections. With its already approved FDA status for the treatment of two diseases and excellent indications and positive results in the treatment of Tuberculosis and MDR-TB and other diseases, IFN-γ has the potential of becoming a lifesaver drug. IFN-γ as a drug is available in majority of developed/developing countries throughout the world; however it is not available in India. A cost effective method for the production of Recombinant Human IFN-γ can reduce the cost of treatment of chronic granulomatous disease and malignant osteopetrosis significantly which currently stands as $50000/year.
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Supervisor: Veeranki Venkata Dasu
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BIOSCIENCES AND BIOENGINEERING