Recombinant Truncated Diphtheria toxin for Possible Therapeutic Applications
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Date
2014
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Abstract
Toxicity of Bacterial toxins , like diphtheria tocin has been widely utilized to create therapeutic agents that can kill target cells. For example, Immunotoxins have been developed by fusing antibodies to diphtheria toxin. Antibodies home the toxin to specific cells, overexpressing the antigens and the toxin kills the target cells. Many of these toxins have receptors on certain cells. However, the receptor-binding ability of such toxins remains largely unutilized.
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Supervisor: Biplab Bose
Keywords
BIOSCIENCES AND BIOENGINEERING