Design Synthesis and Applications of Fluorescent Small Organic Molecules and Nucleoside

Abstract

The dissertation entitled Design synthesis and applications of fluorescent Small Organic Molecules and Nucleoside' is an embodiment of research aimed aimed towards: (a) the importance of small organic solvatochromic fluorophores and fluorescent nucleosides, (b) the use of ''Click'' reaction and Sonogashira coupling to the design and synthesis of solvatochromic fluorophores and fluorescent nucleoside, (c) probing of biomolecular (Protein and DNA) and micellar microenvironment with small fluorescent molecules, (d) the detection of metal ions , and (e) the tetection DNA with fluorescently labeled oligonucleotide probes. ...