Synthesis of nitrogen and oxygen heterocyclic compounds

Abstract

The content of this thesis has been divided into five chapters based on the results of experimental work done during the course of the research period. The chapter 1 of the thesis represents an introduction to nitrogen and oxygen heterocyclic compounds, their biological utility and significance as well as experimental synthesis. Chapter 2 describes regioselective synthesis of dihydropyran derivatives via oxonium-ene cyclization reaction. Chapter 3 represents regio- and diastereo-selective synthesis of substituted pyrano-pyrans from β-allenols and aldehydes. Chapter 4 deals with stereo- and regio-selective synthesis of substituted pyrollidines mediated by Indium (III) chloride. Chapter 5 is about intramolecular cyclization of N-tethered alkenol-benzyls via Friedel Craft type reaction.