Browsing by Author "Kumar, Satish"
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Item Exploring the structure and dynamics fo proteins in non-native states using fluorescence spectroscopy(2008) Kumar, SatishIn the present thesis, structure and dynamics of non-native states in proteins are discussed under different experimental conditions. Owing to their conformation heterogeneity their involvement in protein folding pathway including their role in different protein misfolding diseases, non-native forms of protein are important both for basic and applied areas of biological science. Local structures in protein under extreme denaturing conditions are known as residual structures and are believed to act as nucleation site for protein folding events. Locating these structures are important to reveal protein folding/unfolding events. I used fluorescence from trp(s) as a simple and sensitive tool to hunt for these structures in different proteins, namely, barstar, subtilisin carlsberg (SC), human serum albumin (HSA), melittin, myelin basic protein (MBP), glucagon, Ribonuclease T1 (RNase T1), Trp-Met-Asp-Phe, bovine serum albumin (BSA) and hen egg white lysozyme (HEWL) after nightlong (~12 hours) incubation in 6 M GdnCl at room temperature. Except BSA and HEWL all other proteins used here contain single trp per polypeptide chain..Item Resource allocation strategies for multimedia services in cellular networks(2017) Kumar, SatishThe ever increasing demand for high bandwidth, low latency multimedia applications on mobile devices is set to pose an enormous challenge on the bandwidth allocation and multiplexing mechanisms in Long Term Evolution (LTE) and future wireless networks. In order to face this challenge, these cellular network infrastructures must be empowered with sophisticated but low overhead online radio resource allocation mechanisms to efficiently serve a variety of heterogeneous user equipments (mobile phones, laptops, tablets etc.) such that the Quality of Service (QoS)/Quality of Experience (QoE) demands of all flows/end-users are met. In addition to satisfying QoS/QoE, the resource scheduling mechanisms may also need to simultaneously cater to other practical constraints/objectives like limited power budget, maximizing spectral efficiency and graceful degradation in times of overload, in the face of ever changing network dynamics, user mobility etc. In this dissertation, we present a few novel scheduling methodologies for system level as well as client centric QoS/QoE management corresponding to multimedia streaming over cellular networks in general, and LTE based systems in particular.