Browsing by Author "Chandra, Jyoti"

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    Development of greener coupling reagents and methodologies for the syntheses of Esters, Amides and Peptides
    (2018) Chandra, Jyoti
    The contents of this thesis have been divided into six chapters. Chapter 1 contains the introduction. Chapter 2 contains the detailed studies on the halogen-free synthesis of sulphonates of alcohol, Oxyma-O-sulphonates, and oxime-O-sulphonates under microwave irradiation. Chapter 3 contains our works on the greener approach towards the synthesis of amides and esters using the catalytic amount of o-NosylOXY. Chapter 4 contains the racemization free synthesis of peptides and polypeptides using the sub-stoichiometric amount of o-NosylOXY. The research works on the synthesis of 1,2,4-oxadiazoles by using the catalytic amount of o-NosylOXY is incorporated in the Chapter 5. Our efforts on the development of a new generation of an efficient coupling reagent, TCBOXY, for the synthesis of esters, thioesters, amides, and peptides are incorporated in the Chapter 6.