Bhattacharjee, Mitradip2020-08-062023-10-262020-08-062023-10-262018ROLL NO.136153001https://gyan.iitg.ac.in/handle/123456789/1537Supervisor: Dipankar Bandyopadhyay and Harshal B. NemadeThe number of patients worldwide are increasing at an alarming rate and thus the burden on secondary and tertiary healthcare system are increasing day by day. In order to meet the demand for healthcare facilities, it is now extremely important to strengthen the primary health care system. In this direction development of point-of-care-testing (POCT) devices for on-site and early detection is extremely important. The research work of this thesis focuses on the development of affordable, rapid, user-friendly point-of-care testing sensors and devices harnessing the attributes of nanotechnology, electronic devices, wearable and flexible electronics, and microfluidics for healthcare applications. Multiple devices and sensors were developed for the early diagnosis of chronic obstructive pulmonary devices (COPD), neurological disorders, eye-related diseases, cancers among others. A section of the research work also addressed non-conventional microfluidic electrical energy harvester based on zeta potential. The research work also includes nanostructure based back-gated FET and spintronics based magnetoresistive device for sensing application. The research work also involves few simulations in atomistic toolkit, COMSOL and Matlab to understand the physics associated with the phenomenon. Moreover, several fabrication and characterization instruments such as FESEM, Mask Writer, Electron Beam Lithography (EBL), Thermal Evaporation Deposition System, Optical microscope, Raman spectroscopy, XRD, UV-Vis spectroscopy, FTIR, sourcemeter, digital multimeter digital oscilloscope, and other small electronic instruments were an integral part of this research work.enNANOTECHNOLOGYThesis