Kannan, M.2017-10-202023-10-192017-10-202023-10-192016ROLL NO.10612222https://gyan.iitg.ac.in/handle/123456789/839Supervisor: T. PunniyamurthyThe thesis contains four chapters. Chapter I describes a brief literature survey on asymmetric metal catalysis utilizing chiral tetradentate salen, salan, salelan ligands and tridentate ?-aminoalcohol derived ligands. Chapter II focuses on the sythesis of chiral Cu(II)-complexes bearing salen, salan, salalen and salalan ligands and their application towards enantioselective nitroaldol reaction. The reaction is mild and afforded aryl, heteroaryl, naphthyl and alkyl ?-nitroalcohols in high enantioselectivities at room temperature without any additivies. Chapter III presents the synthesis of chiral tetradentate salen ligand and tridentate ?-aminoalcohol derived ligands for Fe-catalyzed enantioselective thia-Michael-aldol cascade reaction. The reaction proceeded readily between aryl, heteroaryl, alkyl chalcones and 1,4-dithiane-2,5-diol in the presence of Fe-catalyst to afford the corresponding trisubstituted tetrahydrothiophenes in good enantioselectivities.enCHEMISTRYThesis