Studies Toward Copper-Catalyzed Asymmetric Nitroaldol and Iron-Catalyzed Thia-Michael/Aldol Cascade Reactions
| dc.contributor.author | Kannan, M. | |
| dc.date.accessioned | 2017-10-20T06:52:52Z | |
| dc.date.accessioned | 2023-10-19T12:09:43Z | |
| dc.date.available | 2017-10-20T06:52:52Z | |
| dc.date.available | 2023-10-19T12:09:43Z | |
| dc.date.issued | 2016 | |
| dc.description | Supervisor: T. Punniyamurthy | en_US |
| dc.description.abstract | The thesis contains four chapters. Chapter I describes a brief literature survey on asymmetric metal catalysis utilizing chiral tetradentate salen, salan, salelan ligands and tridentate ?-aminoalcohol derived ligands. Chapter II focuses on the sythesis of chiral Cu(II)-complexes bearing salen, salan, salalen and salalan ligands and their application towards enantioselective nitroaldol reaction. The reaction is mild and afforded aryl, heteroaryl, naphthyl and alkyl ?-nitroalcohols in high enantioselectivities at room temperature without any additivies. Chapter III presents the synthesis of chiral tetradentate salen ligand and tridentate ?-aminoalcohol derived ligands for Fe-catalyzed enantioselective thia-Michael-aldol cascade reaction. The reaction proceeded readily between aryl, heteroaryl, alkyl chalcones and 1,4-dithiane-2,5-diol in the presence of Fe-catalyst to afford the corresponding trisubstituted tetrahydrothiophenes in good enantioselectivities. | en_US |
| dc.identifier.other | ROLL NO.10612222 | |
| dc.identifier.uri | https://gyan.iitg.ac.in/handle/123456789/839 | |
| dc.language.iso | en | en_US |
| dc.relation.ispartofseries | TH-1590; | |
| dc.subject | CHEMISTRY | en_US |
| dc.title | Studies Toward Copper-Catalyzed Asymmetric Nitroaldol and Iron-Catalyzed Thia-Michael/Aldol Cascade Reactions | en_US |
| dc.type | Thesis | en_US |
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