Synthesis of complex nitrogen heterocyclic compounds

No Thumbnail Available
Date
2017
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
The contents of this thesis have been divided into five chapters based on the results of experimental work performed during the complete course of the research period. The chapter 1 mainly discusses about synthetic strategy and utility of propargylamines. Chapter 2 describes regioselective one-pot, three-component synthesis of substituted 2H-indazoles from 2-nitroarylaldehyde, alkyne and amine catalyzed by CuBr/Zn(OTf)2 system. Chapter 3 illustrates Ag(OTf) catalyzed synthesis of substituted pyrazole N-oxides and pyrazoles from propargylamines. Chapter 4 demonstrates synthesis of highly substituted 4-iodopyrazole Noxides and pyrazoles from propargylamines. Chapter 5 explains that, a facile synthesis of benzo[1,4]oxazepine fused tetrahydroisoquinoline and tetrahydro-β-carboline analogues via Pictet-Spengler reaction of intramolecular cyclic iminium ion intermediates. Each chapter constitute four sections, describing introduction, present work, experimental work and spectral data, respectively.
Description
Supervisor: Anil K Saikia
Keywords
CHEMISTRY
Citation