Exploring Synthesis of Functionalized Tetrahydroquinoline and N-substituted Hydrazine via a Reductive Process Using Hantzsch Ester as Hydrogen Source

Abstract

The present thesis, entitled “Exploring synthesis of functionalized tetrahydroquinoline and N-substituted hydrazine via a reductive process using Hantzsch ester as hydrogen source” is divided into six chapters based on the results obtained from the experimental works during the course of PhD research period.

Chapter 1 includes brief introduction of boronic acid catalysis (BAC) and hexafluoroisopropanol (HFIP), and their utilization in organic synthesis, particularly in reduction chemistry. It highlights how BAC and HFIP contribute to improving reaction efficiency and selectivity.