Synthesis of Nitrogenous Heterocycles via Multicomponent Reaction and Exploration of Naphthalen-2-ol Sulfides to Access Benzylic Ethers & Naphthofurans

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dc.contributor.author Islam, Kobirul
dc.date.accessioned 2017-10-20T07:04:11Z
dc.date.available 2017-10-20T07:04:11Z
dc.date.issued 2016
dc.identifier.other ROLL NO.11612215
dc.identifier.uri http://gyan.iitg.ernet.in/handle/123456789/840
dc.description Supervisor:Abu T. Khan and Mohammad Qureshi en_US
dc.description.abstract The contents of this thesis entitled “Synthesis of Nitrogenous Heterocycles via Multicomponent Reaction and Exploration of Naphthalen-2-ol Sulfides to Access Benzylic Ethers & Naphthofurans”. Multicomponent reactions are elegant process for the synthesis of various six member nitrogen containing organic frameworks. Different approaches have been developed and applied to construct a wide collection of these heterocyclic moieties. The first four chapter contains an introduction and nitrogenous heterocycles synthesis.using MCR approaches. Chapter I focuses on the synthesis of an important class of nitrogen heterocycles, 1,4-dihydropyridine found in numerous synthetic pharmaceutical agents. This chapter shows synthesis of 5,6-unsubstituted 1,4-dihydropyridine derivatives through one pot three-component reaction from ?,?-unsaturated aldehydes, amines and 1,3-diketones in methanol at room temperature using hydrated ferric sulfate as recyclable catalyst. In Chapter III explore of our synthesized C5-C6-unsubstituted 1,4-dihydropyridines for the construction of exo-hexahydro-1H-chromeno[3,4-h][1,6] naphthyridine-3-carboxylates via stereoselective Povarov reaction using 3-aminocoumarins, aldehydes and 5,6-unsubstituted 1,4-dihydropyridine derivatives employing 10 mol% of Yb(OTf)3. en_US
dc.language.iso en en_US
dc.relation.ispartofseries TH-1591;
dc.subject CHEMISTRY en_US
dc.title Synthesis of Nitrogenous Heterocycles via Multicomponent Reaction and Exploration of Naphthalen-2-ol Sulfides to Access Benzylic Ethers & Naphthofurans en_US
dc.type Thesis en_US


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